Organic depression is a distinct type of depression that comes with apathy, low motivation, increased anger, and impulsive behavior; it usually develops after a brain injury that causes loss of consciousness. Accidents, infections, poisoning, strokes, and trauma can all injure the brain, disrupting brain pathways and disturbing emotions and thoughts. For example, football players who have had previous brain concussions are three times more likely to be given a diagnosis of depression than other people.
Nevertheless, brain injury is different from unipolar major depression and needs different treatment. Sometimes brain injury responds to psychotherapy and small doses of antidepressants or medicines used to treat epileptic seizures.