What is the newest development in modern anti depressants?

Other than MAOIs, modern antidepressants mainly stimulate one or two of the three main neurochemicals involved in depression. Triple reuptake blockers (TRIs) increase all three neurotransmitters: serotonin, norepinephrine, and dopamine. Such triple reuptake inhibitors will probably work faster and have greater effectiveness with fewer side effects than the antidepressants we have now. Several examples are listed in the table.