Tissue transplanted or implanted into a human recipient from a donor of another species, also called a xenotransplant. fetal porcine brain cell transplant, in which dopaminergic neurons from fetal pigs are transplanted into the brain of a person with Parkinson’s, is a xenograft procedure being explored as an investigational treatment for Parkinson’s disease. Xenograft tissues are generally more available than allograft tissues, are taken from human donors. As well, they present fewer risks of infection, as most pathogens (disease-causing substances) are species-specific. Conversely, it is much more difficult for the body to not reject tissue that is from another species.
See also autograft; bioethics; clinical research studies; neural graft; stem cell.